Dosage ; Hypertension: 5mg daily initially (max. 40mg daily).
Heart failure - 2.5mg daily. Maintenance: 10-20mg daily
Combinations ; - see below
1. Enalapril maleate/Hydrochlorthiazide
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| BQL | Zydus Cadila Healthcare | C.Mehta & Co Ltd. | 5mg | 100 | Tablet | per tablet | KES 150.00 |
| Cardace | Cosmos Limited. | Cosmos Limited | 5mg | 28 | Tablet | per tablet | KES 120 |
| Cardace | Cosmos Limited. | Cosmos Limited | 10mg | 28 | Tablet | per tablet | KES 210 |
| Cardace | Cosmos Limited. | Cosmos Limited | 20mg | 28 | Tablet | per tablet | KES 300.00 |
| Cortec | Nabiqasim Industries (Pvt) Ltd | Globe Pharmacy Ltd., | 5mg | 30 | Tablet | per tablet | KES 87 |
| Cortec | Nabiqasim Industries (Pvt) Ltd | Globe Pharmacy Ltd., | 5mg | 100 | Tablet | per tablet | KES 290.50 |
| Cortec | Nabiqasim Industries (Pvt) Ltd | Globe Pharmacy Ltd., | 10mg | 30 | Tablet | per tablet | KES 117 |
| Cortec | Nabiqasim Industries (Pvt) Ltd | Globe Pharmacy Ltd., | 10mg | 100 | Tablet | per tablet | KES 382.00 |
| Emilie | Modern Pharma Ltd. | Metro Pharmaceuticals Ltd. | 5mg | 30 | Tablet | per tablet | KES 130 |
| Emilie | Modern Pharma Ltd. | Metro Pharmaceuticals Ltd. | 10mg | 30 | Tablet | per tablet | KES 170 |
| Emilie | Modern Pharma Ltd. | Metro Pharmaceuticals Ltd. | 20mg | 30 | Tablet | per tablet | KES 220 |
| Enalapril | Agio Pharmaceuticals Limited | Surgilinks Ltd. | 2.5mg | 28 | Tablet | per tablet | KES 220 |
| Enalapril | Agio Pharmaceuticals Limited | Surgilinks Ltd. | 5mg | 28 | Tablet | per tablet | KES 350 |
| Enalapril | Agio Pharmaceuticals Limited | Surgilinks Ltd. | 10mg | 28 | Tablet | per tablet | KES 450 |
| Enalapril | Agio Pharmaceuticals Limited | Surgilinks Ltd. | 20mg | 28 | Tablet | per tablet | KES 650 |
| Enalapril | Agio Pharmaceuticals Limited | Surgilinks Ltd. | 10mg | 100 | Tablet | per tablet | KES 292 |
| Enam | Dr. Reddys Laboratories Ltd. | Surgilinks Ltd. | 5mg | 20 | Tablet | per tablet | KES 154 |
| Enam | Dr. Reddys Laboratories Ltd. | Surgilinks Ltd. | 10mg | 20 | Tablet | per tablet | KES 264 |
| Enapril | Intas Pharmaceuticals Ltd | Unicorn Pharma (K) Ltd. | 5mg | 100 | Tablet | per tablet | KES 515.00 |
| Enapril | Intas Pharmaceuticals Ltd | Unicorn Pharma (K) Ltd. | 10mg | 30 | Tablet | per tablet | KES 1,081.00 |
| Enapril | Intas Pharmaceuticals Ltd | Unicorn Pharma (K) Ltd. | 20mg | 100 | Tablet | per tablet | KES 2,200.00 |
| Enaril- | Beximco Pharma | Madawa Pharmaceuticals Ltd. | 5mg | 100 | Tablet | per tablet | KES 500 |
| Encardil | Medley Pharmaceticals Ltd | Harley's Limited | 5mg | 100 | Tablet | per tablet | KES 360.00 |
| Encardil | Medley Pharmaceticals Ltd | Harley's Limited | 10mg | 100 | Tablet | per tablet | KES 535 |
| Enril | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 5mg | 30 | Tablet | per tablet | KES 120.00 |
| Enril | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 10mg | 30 | Tablet | per tablet | KES 240.00 |
| Enril | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 20mg | 30 | Tablet | per tablet | KES 360.00 |
| Envas | Cadila Pharmaceuticals Ltd. | Cadila Pharmaceuticals (EA) | 2.5mg | 100 | Tablet | per tablet | KES 360 |
| Envas | Cadila Pharmaceuticals Ltd. | Cadila Pharmaceuticals (EA) | 5mg | 100 | Tablet | per tablet | KES 820.00 |
| Envas | Cadila Pharmaceuticals Ltd. | Cadila Pharmaceuticals (EA) | 10mg | 100 | Tablet | per tablet | KES 1,350.00 |
| E-pril | Orchid Healthcare | Sunpar Pharmaceuticals Ltd. | 5mg | 50 | Tablet | per tablet | KES 240 |
| E-pril | Orchid Healthcare | Sunpar Pharmaceuticals Ltd. | 10mg | 50 | Tablet | per tablet | KES 400 |
| Flaminopril | Flamingo Heat Pad | Harley's Limited | 5mg | 100 | Tablet | per tablet | KES 300.00 |
| Flaminopril | Flamingo Heat Pad | Harley's Limited | 10mg | 100 | Tablet | per tablet | KES 450 |
| Invoril | Ranbaxy Laboratories | Pharma Specialities Ltd. | 5mg | 100 | Tablet | per tablet | KES 453 |
| Invoril | Ranbaxy Laboratories | Pharma Specialities Ltd. | 10mg | 100 | Tablet | per tablet | KES 867.00 |
| Korandil | Remedica Ltd. | Twokay Chemicals Ltd | 5mg | 100 | Tablet | per tablet | KES 450.00 |
| Korandil | Remedica Ltd. | Twokay Chemicals Ltd | 10mg | 100 | Tablet | per tablet | KES 650.00 |
| Priloten | Global Napi Pharmaceuticals | Surgilinks Ltd. | 5mg | 100 | Tablet | per tablet | KES 220.00 |
| Priloten | Global Napi Pharmaceuticals | Surgilinks Ltd. | 10mg | 100 | Tablet | per tablet | KES 385.00 |
| Vasopril | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 5mg | 100 | Tablet | per tablet | KES 350.00 |
| Vasopril | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 5mg | 14 | Tablet | per tablet | KES 311 |
| Vasopril | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 10mg | 50 | Tablet | per tablet | KES 311 |
| Vasopril | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 10mg | 100 | Tablet | per tablet | KES 500.00 |
| Ena-denk | Denk Pharma | Laborex Kenya Eurapharma Ltd | 10mg | 30 | Tablet | per tablet | KES 611.76 |
| Ena-denk | Denk Pharma | Laborex Kenya Eurapharma Ltd | 20mg | 30 | Tablet | per tablet | KES 1,044.00 |
| Enaril-5 | Beximco Pharma | Madawa Pharmaceuticals Ltd. | 5mg | 100 | Tablet | per tablet | KES 500.00 |
| Nuril | USV | Surgipharm Ltd | 5mg | 100 | Tablet | per tablet | KES 380.00 |
| Nuril | USV | Surgipharm Ltd | 10mg | 100 | Tablet | per tablet | KES 633.00 |
| Enalapril More info | |
|---|---|
| Mode Of Action | Inhibition of the conversion of angiotensin I to angiotensin II. |
| Drug Indication | Hypertension, heart failure |
| Precautions | Severe CCF, impaired renal function, lactation, aortic stenosis, NSAIDs, monitor serum lithium levels, first dose may cause hypotension especially in dehydrated cases, low sodium serum levels, diuretic treated cases, monitor renal function, may potentiate hypoglyceamic effects of insulin or oral hypoglycaemic agents, haematological monitoring. Avoid potassium sparing diuretics or potassium supplements. |
| Contra-Indications | Pregnancy, history of angioneurotic oedema with previous ACE inhibitors, hypersensitivity, renal vascular disease, porphyria. |
| Side Effects | Persistent dry cough, voice changes, chest pain, taste disturbances, bronchospasm, blood dyscrasias, tachycardia, increased serum potassium levels, anaphylactic reactions, hepatic /renal impairment, hypotension, GI disturbances, muscle cramps, sleep disturbances, flushing, asthenia, impotence, CVS disorders. |
| Dosage | Hypertension: 5mg daily initially (max. 40mg daily). Heart failure - 2.5mg daily. Maintenance: 10-20mg daily. |
| Pregnancy Category | Category D |
| Pregnancy Category Description | Drugs, which have caused, are suspected to have caused, or may be expected to cause an increased rise in the frequency of malformations or irreversible damage. These drugs may also have adverse pharmacological effects required required |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Angiotensin-converting enzyme inhibitors |
Combinations ;
1. Enalapril maleate/Hydrochlorthiazide |
|
|---|---|
| Mode Of Action | Inhibition of the conversion of angiotensin I to angiotensin II and diuresis |
| Drug Indication | Hypertension |
| Precautions | see under enalapril maleate and hydrochlorthiazide |
| Side Effects | see under enalapril maleate and hydrochlorthiazide |
| Dosage | ACE inhibitor / thiazide diuretic to be used in-patients stabilized on the individual components in the same proportions |
| Pregnancy Category | Category D |
| Pregnancy Category Description | Drugs, which have caused, are suspected to have caused, or may be expected to cause an increased rise in the frequency of malformations or irreversible damage. These drugs may also have adverse pharmacological effects required required |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Enril-H | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 20mg/12.5mg | 28 | Tablet | per tablet | KES 640 |
| Enril-H | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 20mg/12.5mg | 30 | Tablet | per tablet | KES 480.00 |
| Vasopril | Nabiqasim Industries (Pvt) Ltd | Harley's Limited | 10mg/25mg | 100 | Tablet | per tablet | KES 544.50 |
| Enapril-H | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 20mg/12.5mg | 30 | Tablet | per tablet | KES 1,490.00 |
| Enril+HCT | Denk Pharma | Laborex Kenya Eurapharma Ltd | 20mg/12.5mg | 30 | Tablet | per tablet | KES 976.00 |